Smoother: on-the-fly processing of interactome data using prefix sums

"Smoother: On-the-fly processing of interactome data using prefix sums" has been published in Nucleic Acids Research. Check it out to learn how Hi-C and RADICL-seq data can be processed and visualized using an interactive interface.

In this paper, we use a prefix-sum index to process interactome data within seconds. On top of the index, we have built a GUI that allows interactive filtering (e.g. by mapping quality), various normalizations (e.g. ICing), and downstream analysis (e.g. virtual 4C).

Here is the GitHub repo: https://github.com/Siegel-Lab/BioSmoother.

Schmidt MR*, Barcons-Simon A, Rabuffo C, Siegel TN* (2024)
Smoother: on-the-fly processing of interactome data using prefix sums.
Nucleic Acids Research 52: e23 doi: 10.1093/nar/gkae008

members of the Siegel lab are listed in bold
* corresponding authors